Page last updated on 25th February 2020

Identification of a Nonsense-Mediated Decay pathway at the Endoplasmic Reticulum
Longman D, Jackson-Jones KA, Maslon MM, Murphy LC, Young RS, Stoddart JJ, Taylor MS, Papadopoulos DK, Caceres JF.
bioRxiv 2020 doi: 10.1101/2020.02.24.954453

Pervasive lesion segregation shapes cancer genome evolution
Aitken SJ, Anderson CJ, Connor F, Pich O, Sundaram V, Feig C, Rayner TF, Lukk M, Aitken S, Luft J, Kentepozidou E, Arnedo-Pac C, Beentjes S, Davies SE, Drews RM, Ewing A, Kaiser VB, Khamseh A, Lopez-Arribillaga E, Redmond AM, Santoyo-Lopez J, Sentis I, Talmane L, Yates AD, Semple CA, Lopez-Bigas N, Flicek P, Odom DT, Taylor MS
bioRxiv 2019 doi: 10.1101/868679

Functional Annotation of Human Long Non-Coding RNAs via Molecular Phenotyping
Ramilowski J, .. Taylor MS, Young RS, .. de Hoon M, Shin JW , Carninci P.
bioRxiv 2019 doi: 10.1101/700864

Splicing buffers suboptimal codon usage in human cells
Mordstein C, Savisaar R, Young RS, Bazile J, Talmane L, Luft J, Liss M, Taylor MS, Hurst LD, Kudla G.
bioRxiv 2019 doi: 10.1101/527440

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions.
Halachev M, Meynert A, Taylor MS, Vitart V, Kerr SM, Klaric L, S. G. P. Consortium, Aitman TJ, Haley CS, Prendergast JG, Pugh C, Hume DA, Harris SE, Liewald DC, Deary IJ, Semple CA, Wilson JF.
PLoS Genetics 2019 doi:10.1371/journal.pgen.1008480 [PMID:31765389]

RNase H2, mutated in Aicardi-Goutieres syndrome, promotes LINE-1 retrotransposition.
Benitez-Guijarro M, Lopez-Ruiz C, Tarnauskaite Z, Murina O, Mian Mohammad M, Williams TC, Fluteau A, Sanchez L, Vilar-Astasio R, Garcia-Canadas M, Cano D, Kempen MH, Sanchez-Pozo A, Heras SR, Jackson AP, Reijns MA, Garcia-Perez JL.
EMBO J 2018 doi:10.15252/embj.201798506 [PMID:29959219]

Hybridization and gene flow in the mega-pest lineage of moth, Helicoverpa.
Anderson CJ, Oakeshott JG, Tay WT, Gordon KHJ, Zwick A, Walsh TK.
PNAS 2018 doi:10.1073/pnas.1718831115 [PMID:29610329]

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma.
Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH.
Dis Model Mech 2018 doi:10.1242/dmm.031369 [PMID:29361513]

Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers.
Young RS, Kumar Y, Bickmore WA, Taylor MS.
Genome Biology 2017 doi:10.1186/s13059-017-1379-8 [PMID:29284524] Cited by 21

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model.
Moss CF, Dalla Rosa I, Hunt LE, Yasukawa T, Young R, Jones AWE, Reddy K, Desai R, Virtue S, Elgar G, Voshol P, Taylor MS, Holt IJ, Reijns MAM, Spinazzola A.
Nucleic Acids Res 2017 doi:10.1093/nar/gkx1009 [PMID:29106596] Cited by 12

RNA meets DNA: The Potential for gene expression to produce short RNA molecules capable of generating DNA mutation and driving genome evolution (Comment on DOI: 10.1002/bies.201700069).
Young RS.
Bioessays 2017 doi:10.1002/bies.201700141 [PMID:28881391]

Genetic variation and RNA structure regulate microRNA biogenesis.
Fernandez N, Cordiner RA, Young RS, Hug N, Macias S, Caceres JF.
Nature Communications 2017 doi:10.1038/ncomms15114 [PMID:28466845]

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Williams TC, Stewart E.
N Engl J Med 2017 doi:10.1056/NEJMc1615712 [PMID:28249136]

Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types.
Kaiser VB, Taylor MS, Semple CA.
PLoS Genetics 2016 doi:10.1371/journal.pgen.1006207 [PMID:27490693] Cited by 31

Lineage-specific genomics: Frequent birth and death in the human genome: The human genome contains many lineage-specific elements created by both sequence and functional turnover.
Young RS.
Bioessays 2016 doi:10.1002/bies.201500192 [PMID:27231054]

Enhancer Turnover Is Associated with a Divergent Transcriptional Response to Glucocorticoid in Mouse and Human Macrophages.
Jubb AW, Young RS, Hume DA, Bickmore WA.
J Immunol 2016 doi:10.4049/jimmunol.1502009 [PMID:26663721]

Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq.
Ding J, Taylor MS, Jackson AP, Reijns MA.
Nature Protocols 2015 doi:10.1038/nprot.2015.099 [PMID:26313479] Cited by 17

The frequent evolutionary birth and death of functional promoters in mouse and human.
Young RS, Hayashizaki Y, Andersson R, Sandelin A, Kawaji H, Itoh M, Lassmann T, Carninci P, FANTOM Consortium, Bickmore WA, Forrest AR, Taylor MS.
Genome Research 2015 doi:10.1101/gr.190546.115 [PMID:26228054] Cited by 27

Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Kaiser VB, Svinti V, Prendergast JG, Chau YY, Campbell A, Patarcic I, Barroso I, Joshi PK, Hastie ND, Miljkovic A, Taylor MS, Generation Scotland, UK10K, Enroth S, Memari Y, Kolb-Kokocinski A, Wright AF, Gyllensten U, Durbin R, Rudan I, Campbell H, Polasek O, Johansson A, Sauer S, Porteous DJ, Fraser RM, Drake C, Vitart V, Hayward C, Semple CA, Wilson JF.
Human Molecular Genetics 2015 doi:10.1093/hmg/ddv272 [PMID:26173456] Cited by 19

Exome sequencing to detect rare variants associated with general cognitive ability: a pilot study.
Luciano M, Svinti V, Campbell A, Marioni RE, Hayward C, Wright AF, Taylor MS, Porteous DJ, Thomson P, Prendergast JG, Hastie ND, Farrington SM, Scotland G, Dunlop MG, Deary IJ.
Twin Res Hum Genet 2015 doi:10.1017/thg.2015.10 [PMID:25744449] Cited by 10

Lagging-strand replication shapes the mutational landscape of the genome.
Reijns MAM, Kemp H, Ding J, de Proce SM, Jackson AP, Taylor MS.
Nature 2015 doi:10.1038/nature14183 [PMID:25624100] Cited by 130

Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis.
Redshaw N, Huggett JF, Taylor MS, Foy CA, Devonshire AS.
BMC Genomics 2014 doi:10.1186/1471-2164-15-1174 [PMID:25539843] Cited by 25

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nellaker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, Keegan LP, O’Connell MA.
Cell Reports 2014 doi:10.1016/j.celrep.2014.10.041 [PMID:25456137]

SuRFing the genomics wave: an R package for prioritising SNPs by functionality.
Ryan NM, Morris SW, Porteous DJ, Taylor MS, Evans KL.
Genome Medicine 2014 doi:10.1186/s13073-014-0079-1 [PMID:25400697] Cited by 19

A CGG-repeat expansion mutation in ZNF713 causes FRA7A: association with autistic spectrum disorder in two families.
Metsu S, Rainger JK, Debacker K, Bernhard B, Rooms L, Grafodatskaya D, Weksberg R, Fombonne E, Taylor MS, Scherer SW, Kooy RF, FitzPatrick DR.
Human Mutation 2014 doi:10.1002/humu.22683 [PMID:25196122]

Genetic heterogeneity in Cornelia de Lange syndrome (CdLS) and CdLS-like phenotypes with observed and predicted levels of mosaicism.
Ansari M, Poke G, Ferry Q, Williamson K, Aldridge R, Meynert AM, Bengani H, Chan CY, Kayserili H, Avci S, Hennekam RC, Lampe AK, Redeker E, Homfray T, Ross A, Falkenberg Smeland M, Mansour S, Parker MJ, Cook JA, Splitt M, Fisher RB, Fryer A, Magee AC, Wilkie A, Barnicoat A, Brady AF, Cooper NS, Mercer C, Deshpande C, Bennett CP, Pilz DT, Ruddy D, Cilliers D, Johnson DS, Josifova D, Rosser E, Thompson EM, Wakeling E, Kinning E, Stewart F, Flinter F, Girisha KM, Cox H, Firth HV, Kingston H, Wee JS, Hurst JA, Clayton-Smith J, Tolmie J, Vogt J, Tatton-Brown K, Chandler K, Prescott K, Wilson L, Behnam M, McEntagart M, Davidson R, Lynch SA, Sisodiya S, Mehta SG, McKee SA, Mohammed S, Holden S, Park SM, Holder SE, Harrison V, McConnell V, Lam WK, Green AJ, Donnai D, Bitner-Glindzicz M, Donnelly DE, Nellaker C, Taylor MS, FitzPatrick DR.
J Med Genet 2014 doi:10.1136/jmedgenet-2014-102573 [PMID:25125236] Cited by 92

Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.
Zhang Y, Dean C, Chessum L, Nguyen D, Stewart M, Taylor M, Cookson WO, Moffatt MF.
Mamm Genome 2014 doi:10.1007/s00335-014-9535-x [PMID:25091723] Cited by 8

Loss of ALDH18A1 function is associated with a cellular lipid droplet phenotype suggesting a link between autosomal recessive cutis laxa type 3A and Warburg Micro syndrome.
Handley MT, Megarbane A, Meynert AM, Brown S, Freyer E, Taylor MS, Jackson IJ, Aligianis IA.
Mol Genet Genomic Med 2014 doi:10.1002/mgg3.70 [PMID:25077174]

Variant detection sensitivity and biases in whole genome and exome sequencing.
Meynert AM, Ansari M, FitzPatrick DR, Taylor MS.
BMC Bioinformatics 2014 doi:10.1186/1471-2105-15-247 [PMID:25038816] Cited by 164

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A, UK10K, Baylor-Hopkins Center for Mendelian Genomics, Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR.
American Journal of Human Genetics 2014 doi:10.1016/j.ajhg.2014.05.005 [PMID:24906020] Cited by 59

FRA2A is a CGG repeat expansion associated with silencing of AFF3.
Metsu S, Rooms L, Rainger J, Taylor MS, Bengani H, Wilson DI, Chilamakuri CS, Morrison H, Vandeweyer G, Reyniers E, Douglas E, Thompson G, Haan E, Gecz J, Fitzpatrick DR, Kooy RF.
PLoS Genetics 2014 doi:10.1371/journal.pgen.1004242 [PMID:24763282] Cited by 21

A promoter-level mammalian expression atlas.
FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jorgensen M, Dimont E, Arner E, Schmidl C, Schaefer U, Medvedeva YA, Plessy C, Vitezic M, Severin J, Semple C, Ishizu Y, Young RS, Francescatto M, Alam I, Albanese D, Altschuler GM, Arakawa T, Archer JA, Arner P, Babina M, Rennie S, Balwierz PJ, Beckhouse AG, Pradhan-Bhatt S, Blake JA, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Burroughs AM, Califano A, Cannistraci CV, Carbajo D, Chen Y, Chierici M, Ciani Y, Clevers HC, Dalla E, Davis CA, Detmar M, Diehl AD, Dohi T, Drablos F, Edge AS, Edinger M, Ekwall K, Endoh M, Enomoto H, Fagiolini M, Fairbairn L, Fang H, Farach-Carson MC, Faulkner GJ, Favorov AV, Fisher ME, Frith MC, Fujita R, Fukuda S, Furlanello C, Furino M, Furusawa J, Geijtenbeek TB, Gibson AP, Gingeras T, Goldowitz D, Gough J, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Harbers M, Harshbarger J, Hasegawa A, Hasegawa Y, Hashimoto T, Herlyn M, Hitchens KJ, Ho Sui SJ, Hofmann OM, Hoof I, Hori F, Huminiecki L, Iida K, Ikawa T, Jankovic BR, Jia H, Joshi A, Jurman G, Kaczkowski B, Kai C, Kaida K, Kaiho A, Kajiyama K, Kanamori-Katayama M, Kasianov AS, Kasukawa T, Katayama S, Kato S, Kawaguchi S, Kawamoto H, Kawamura YI, Kawashima T, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klinken SP, Knox AJ, Kojima M, Kojima S, Kondo N, Koseki H, Koyasu S, Krampitz S, Kubosaki A, Kwon AT, Laros JF, Lee W, Lennartsson A, Li K, Lilje B, Lipovich L, Mackay-Sim A, Manabe R, Mar JC, Marchand B, Mathelier A, Mejhert N, Meynert A, Mizuno Y, de Lima Morais DA, Morikawa H, Morimoto M, Moro K, Motakis E, Motohashi H, Mummery CL, Murata M, Nagao-Sato S, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nakazato K, van Nimwegen E, Ninomiya N, Nishiyori H, Noma S, Noma S, Noazaki T, Ogishima S, Ohkura N, Ohimiya H, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Pain A, Passier R, Patrikakis M, Persson H, Piazza S, Prendergast JG, Rackham OJ, Ramilowski JA, Rashid M, Ravasi T, Rizzu P, Roncador M, Roy S, Rye MB, Saijyo E, Sajantila A, Saka A, Sakaguchi S, Sakai M, Sato H, Savvi S, Saxena A, Schneider C, Schultes EA, Schulze-Tanzil GG, Schwegmann A, Sengstag T, Sheng G, Shimoji H, Shimoni Y, Shin JW, Simon C, Sugiyama D, Sugiyama T, Suzuki M, Suzuki N, Swoboda RK, ‘t Hoen PA, Tagami M, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tatum Z, Thompson M, Toyodo H, Toyoda T, Valen E, van de Wetering M, van den Berg LM, Verado R, Vijayan D, Vorontsov IE, Wasserman WW, Watanabe S, Wells CA, Winteringham LN, Wolvetang E, Wood EJ, Yamaguchi Y, Yamamoto M, Yoneda M, Yonekura Y, Yoshida S, Zabierowski SE, Zhang PG, Zhao X, Zucchelli S, Summers KM, Suzuki H, Daub CO, Kawai J, Heutink P, Hide W, Freeman TC, Lenhard B, Bajic VB, Taylor MS, Makeev VJ, Sandelin A, Hume DA, Carninci P, Hayashizaki Y.
Nature 2014 doi:10.1038/nature13182 [PMID:24670764] Cited by 707

Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects.
Williamson KA, Rainger J, Floyd JA, Ansari M, Meynert A, Aldridge KV, Rainger JK, Anderson CA, Moore AT, Hurles ME, Clarke A, van Heyningen V, Verloes A, Taylor MS, Wilkie AO, UK10K Consortium, Fitzpatrick DR.
American Journal of Human Genetics 2014 doi:10.1016/j.ajhg.2014.01.001 [PMID:24462371] Cited by 52

Quantifying single nucleotide variant detection sensitivity in exome sequencing.
Meynert AM, Bicknell LS, Hurles ME, Jackson AP, Taylor MS.
BMC Bioinformatics 2013 doi:10.1186/1471-2105-14-195 [PMID:23773188] Cited by 65

Application of next generation qPCR and sequencing platforms to mRNA biomarker analysis.
Devonshire AS, Sanders R, Wilkes TM, Taylor MS, Foy CA, Huggett JF.
Methods 2013 doi:10.1016/j.ymeth.2012.07.021 [PMID:22841564] Cited by 56

Evolution of the human-specific microRNA miR-941.
Hu HY, He L, Fominykh K, Yan Z, Guo S, Zhang X, Taylor MS, Tang L, Li J, Liu J, Wang W, Yu H, Khaitovich P.
Nature Communications 2012 doi:10.1038/ncomms2146 [PMID:23093182] Cited by 86

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Reijns MA, Rabe B, Rigby RE, Mill P, Astell KR, Lettice LA, Boyle S, Leitch A, Keighren M, Kilanowski F, Devenney PS, Sexton D, Grimes G, Holt IJ, Hill RE, Taylor MS, Lawson KA, Dorin JR, Jackson AP.
Cell 2012 doi:10.1016/j.cell.2012.04.011 [PMID:22579044] Cited by 299

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Schroder K, Irvine KM, Taylor MS, Bokil NJ, Le Cao KA, Masterman KA, Labzin LI, Semple CA, Kapetanovic R, Fairbairn L, Akalin A, Faulkner GJ, Baillie JK, Gongora M, Daub CO, Kawaji H, McLachlan GJ, Goldman N, Grimmond SM, Carninci P, Suzuki H, Hayashizaki Y, Lenhard B, Hume DA, Sweet MJ.
PNAS 2012 doi:10.1073/pnas.1110156109 [PMID:22451944] Cited by 195

Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex.
Vandiedonck C, Taylor MS, Lockstone HE, Plant K, Taylor JM, Durrant C, Broxholme J, Fairfax BP, Knight JC.
Genome Research 2011 doi:10.1101/gr.116681.110 [PMID:21628452] Cited by 69

CEP152 is a genome maintenance protein disrupted in Seckel syndrome.
Kalay E, Yigit G, Aslan Y, Brown KE, Pohl E, Bicknell LS, Kayserili H, Li Y, Tuysuz B, Nurnberg G, Kiess W, Koegl M, Baessmann I, Buruk K, Toraman B, Kayipmaz S, Kul S, Ikbal M, Turner DJ, Taylor MS, Aerts J, Scott C, Milstein K, Dollfus H, Wieczorek D, Brunner HG, Hurles M, Jackson AP, Rauch A, Nurnberg P, Karaguzel A, Wollnik B.
Nature Genetics 2011 doi:10.1038/ng.725 [PMID:21131973] Cited by 209

The (non)malignancy of cancerous amino acidic substitutions.
Talavera D, Taylor MS, Thornton JM.
Proteins 2010 doi:10.1002/prot.22574 [PMID:19787769] Cited by 21

Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes.
Taylor JM, Street TL, Hao L, Copley R, Taylor MS, Hayden PJ, Stolper G, Mott R, Hein J, Moffatt MF, Cookson WO.
PLoS One 2009 doi:10.1371/journal.pone.0007651 [PMID:19888454] Cited by 32

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.
FANTOM Consortium, Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, Kanamori-Katayama M, Kubosaki A, Akalin A, Ando Y, Arner E, Asada M, Asahara H, Bailey T, Bajic VB, Bauer D, Beckhouse AG, Bertin N, Bjorkegren J, Brombacher F, Bulger E, Chalk AM, Chiba J, Cloonan N, Dawe A, Dostie J, Engstrom PG, Essack M, Faulkner GJ, Fink JL, Fredman D, Fujimori K, Furuno M, Gojobori T, Gough J, Grimmond SM, Gustafsson M, Hashimoto M, Hashimoto T, Hatakeyama M, Heinzel S, Hide W, Hofmann O, Hornquist M, Huminiecki L, Ikeo K, Imamoto N, Inoue S, Inoue Y, Ishihara R, Iwayanagi T, Jacobsen A, Kaur M, Kawaji H, Kerr MC, Kimura R, Kimura S, Kimura Y, Kitano H, Koga H, Kojima T, Kondo S, Konno T, Krogh A, Kruger A, Kumar A, Lenhard B, Lennartsson A, Lindow M, Lizio M, Macpherson C, Maeda N, Maher CA, Maqungo M, Mar J, Matigian NA, Matsuda H, Mattick JS, Meier S, Miyamoto S, Miyamoto-Sato E, Nakabayashi K, Nakachi Y, Nakano M, Nygaard S, Okayama T, Okazaki Y, Okuda-Yabukami H, Orlando V, Otomo J, Pachkov M, Petrovsky N, Plessy C, Quackenbush J, Radovanovic A, Rehli M, Saito R, Sandelin A, Schmeier S, Schonbach C, Schwartz AS, Semple CA, Sera M, Severin J, Shirahige K, Simons C, St Laurent G, Suzuki M, Suzuki T, Sweet MJ, Taft RJ, Takeda S, Takenaka Y, Tan K, Taylor MS, Teasdale RD, Tegner J, Teichmann S, Valen E, Wahlestedt C, Waki K, Waterhouse A, Wells CA, Winther O, Wu L, Yamaguchi K, Yanagawa H, Yasuda J, Zavolan M, Hume DA, Riken Omics Science Center, Arakawa T, Fukuda S, Imamura K, Kai C, Kaiho A, Kawashima T, Kawazu C, Kitazume Y, Kojima M, Miura H, Murakami K, Murata M, Ninomiya N, Nishiyori H, Noma S, Ogawa C, Sano T, Simon C, Tagami M, Takahashi Y, Kawai J, Hayashizaki Y.
Nature Genetics 2009 doi:10.1038/ng.375 [PMID:19377474] Cited by 397

High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues.
Huang GJ, Shifman S, Valdar W, Johannesson M, Yalcin B, Taylor MS, Taylor JM, Mott R, Flint J.
Genome Research 2009 doi:10.1101/gr.088120.108 [PMID:19376938] Cited by 77

Molecular biology. The structure of change.
Semple CA, Taylor MS.
Science 2009 doi:10.1126/science.1169408 [PMID:19150834] Cited by 10

Rapidly evolving human promoter regions.
Taylor MS, Massingham T, Hayashizaki Y, Carninci P, Goldman N, Semple CA.
Nature Genetics 2008 doi:10.1038/ng1108-1262 [PMID:18957975] Cited by 23

Expression of the fras1/frem gene family during zebrafish development and fin morphogenesis.
Gautier P, Naranjo-Golborne C, Taylor MS, Jackson IJ, Smyth I.
Developmental Dynamics 2008 doi:10.1002/dvdy.21729 [PMID:18816440] Cited by 16

Singleton SNPs in the human genome and implications for genome-wide association studies.
Ke X, Taylor MS, Cardon LR.
Eur J Hum Genet 2008 doi:10.1038/sj.ejhg.5201987 [PMID:18197193] Cited by 46

Development and evaluation of a real-time PCR assay for detection of Pneumocystis jirovecii DNA in bronchoalveolar lavage fluid of HIV-infected patients.
Huggett JF, Taylor MS, Kocjan G, Evans HE, Morris-Jones S, Gant V, Novak T, Costello AM, Zumla A, Miller RF.
Thorax 2008 doi:10.1136/thx.2007.081687 [PMID:17693588] Cited by 121

Identification of common genetic variation that modulates alternative splicing.
Hull J, Campino S, Rowlands K, Chan MS, Copley RR, Taylor MS, Rockett K, Elvidge G, Keating B, Knight J, Kwiatkowski D.
PLoS Genetics 2007 doi:10.1371/journal.pgen.0030099 [PMID:17571926] Cited by 153

Management, presentation and interpretation of genome scans using GSCANDB.
Taylor M, Valdar W, Kumar A, Flint J, Mott R.
Bioinformatics 2007 doi:10.1093/bioinformatics/btm123 [PMID:17400728] Cited by 5

Problems of developing molecular diagnostic tests for opportunistic pathogens: the example of Pneumocystis jirovecii.
Huggett JF, Miller RF, Taylor MS, Costello AM, Zumla A.
J Eukaryot Microbiol 2006 doi:10.1111/j.1550-7408.2006.00182.x [PMID:17169078]

A high-resolution single nucleotide polymorphism genetic map of the mouse genome.
Shifman S, Bell JT, Copley RR, Taylor MS, Williams RW, Mott R, Flint J.
PLoS Biology 2006 doi:10.1371/journal.pbio.0040395 [PMID:17105354] Cited by 263

Genome-wide genetic association of complex traits in heterogeneous stock mice.
Valdar W, Solberg LC, Gauguier D, Burnett S, Klenerman P, Cookson WO, Taylor MS, Rawlins JN, Mott R, Flint J.
Nature Genetics 2006 doi:10.1038/ng1840 [PMID:16832355] Cited by 528

Heterotachy in mammalian promoter evolution.
Taylor MS, Kai C, Kawai J, Carninci P, Hayashizaki Y, Semple CA.
PLoS Genetics 2006 doi:10.1371/journal.pgen.0020030 [PMID:16683025] Cited by 116

Genome-wide analysis of mammalian promoter architecture and evolution.
Carninci P, Sandelin A, Lenhard B, Katayama S, Shimokawa K, Ponjavic J, Semple CA, Taylor MS, Engstrom PG, Frith MC, Forrest AR, Alkema WB, Tan SL, Plessy C, Kodzius R, Ravasi T, Kasukawa T, Fukuda S, Kanamori-Katayama M, Kitazume Y, Kawaji H, Kai C, Nakamura M, Konno H, Nakano K, Mottagui-Tabar S, Arner P, Chesi A, Gustincich S, Persichetti F, Suzuki H, Grimmond SM, Wells CA, Orlando V, Wahlestedt C, Liu ET, Harbers M, Kawai J, Bajic VB, Hume DA, Hayashizaki Y.
Nature Genetics 2006 doi:10.1038/ng1789 [PMID:16645617] Cited by 1252

Genomic anatomy of the Tyrp1 (brown) deletion complex.
Smyth IM, Wilming L, Lee AW, Taylor MS, Gautier P, Barlow K, Wallis J, Martin S, Glithero R, Phillimore B, Pelan S, Andrew R, Holt K, Taylor R, McLaren S, Burton J, Bailey J, Sims S, Squares J, Plumb B, Joy A, Gibson R, Gilbert J, Hart E, Laird G, Loveland J, Mudge J, Steward C, Swarbreck D, Harrow J, North P, Leaves N, Greystrong J, Coppola M, Manjunath S, Campbell M, Smith M, Strachan G, Tofts C, Boal E, Cobley V, Hunter G, Kimberley C, Thomas D, Cave-Berry L, Weston P, Botcherby MR, White S, Edgar R, Cross SH, Irvani M, Hummerich H, Simpson EH, Johnson D, Hunsicker PR, Little PF, Hubbard T, Campbell RD, Rogers J, Jackson IJ.
PNAS 2006 doi:10.1073/pnas.0600199103 [PMID:16505357] Cited by 31

The transcriptional landscape of the mammalian genome.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network .
Science 2005 doi:10.1126/science.1112014 [PMID:16141072] Cited by 3177

Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs.
Jadeja S, Smyth I, Pitera JE, Taylor MS, van Haelst M, Bentley E, McGregor L, Hopkins J, Chalepakis G, Philip N, Perez Aytes A, Watt FM, Darling SM, Jackson I, Woolf AS, Scambler PJ.
Nature Genetics 2005 doi:10.1038/ng1549 [PMID:15838507] Cited by 134

Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans.
Bishop T, Lau KW, Epstein AC, Kim SK, Jiang M, O’Rourke D, Pugh CW, Gleadle JM, Taylor MS, Hodgkin J, Ratcliffe PJ.
PLoS Biology 2004 doi:10.1371/journal.pbio.0020289 [PMID:15361934] Cited by 146

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.
Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ.
PNAS 2004 doi:10.1073/pnas.0402760101 [PMID:15345741] Cited by 100

Occurrence and consequences of coding sequence insertions and deletions in Mammalian genomes.
Taylor MS, Ponting CP, Copley RR.
Genome Research 2004 doi:10.1101/gr.1977804 [PMID:15059996] Cited by 119

Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Egan A, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D’Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Alba M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hubner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, Lopez-Otin C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium.
Nature 2004 doi:10.1038/nature02426 [PMID:15057822] Cited by 2058

Sequence characterization of teleost fish melanocortin receptors.
Logan DW, Bryson-Richardson RJ, Taylor MS, Currie P, Jackson IJ.
Ann N Y Acad Sci 2003 doi:10.1111/j.1749-6632.2003.tb03196.x [PMID:12851332] Cited by 31

The structure and evolution of the melanocortin and MCH receptors in fish and mammals.
Logan DW, Bryson-Richardson RJ, Pagan KE, Taylor MS, Currie PD, Jackson IJ.
Genomics 2003 doi:10.1016/s0888-7543(02)00037-x [PMID:12620396] Cited by 134

Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins.
Seeger M, Hartmann-Petersen R, Wilkinson CR, Wallace M, Samejima I, Taylor MS, Gordon C.
J Biol Chem 2003 doi:10.1074/jbc.M208281200 [PMID:12615927] Cited by 83

Evolutionary constraints on the Disrupted in Schizophrenia locus.
Taylor MS, Devon RS, Millar JK, Porteous DJ.
Genomics 2003 doi:10.1016/s0888-7543(02)00026-5 [PMID:12573262] Cited by 100

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schonbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group Phase I & II Team.
Nature 2002 doi:10.1038/nature01266 [PMID:12466851] Cited by 1768

Sushi gets serious: the draft genome sequence of the pufferfish Fugu rubripes.
Taylor MS, Semple CA.
Genome Biology 2002 doi:10.1186/gb-2002-3-9-reviews1025 [PMID:12225591] Cited by 6

The severe G480C cystic fibrosis mutation, when replicated in the mouse, demonstrates mistrafficking, normal survival and organ-specific bioelectrics.
Dickinson P, Smith SN, Webb S, Kilanowski FM, Campbell IJ, Taylor MS, Porteous DJ, Willemsen R, de Jonge HR, Farley R, Alton EW, Dorin JR.
Human Molecular Genetics 2002 doi:10.1093/hmg/11.3.243 [PMID:11823443] Cited by 33

Characterization and comparative analysis of the EGLN gene family.
Taylor MS.
Gene 2001 doi:10.1016/s0378-1119(01)00633-3 [PMID:11574160] Cited by 165

More biology from the sequence.
Taylor MS.
Genome Biology 2001 doi:10.1186/gb-2001-2-8-reports4018 [PMID:11532209] Cited by 2

The meso-genomic era.
Semple CA, Taylor MS, Ballereau S.
Genome Biology 2001 doi:10.1186/gb-2001-2-7-reports4015 [PMID:11516332] Cited by 7

Genomic sequence analysis of Fugu rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7.
Davidson H, Taylor MS, Doherty A, Boyd AC, Porteous DJ.
Genome Research 2000 doi:10.1101/gr.10.8.1194 [PMID:10958637] Cited by 34

Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, St Clair DM, Muir WJ, Blackwood DH, Porteous DJ.
Human Molecular Genetics 2000 doi:10.1093/hmg/9.9.1415 [PMID:10814723] Cited by 1343

Isolation and characterization of the mouse translin-associated protein X (Trax) gene.
Devon RS, Taylor MS, Millar JK, Porteous DJ.
Mamm Genome 2000 doi:10.1007/s003350010074 [PMID:10790540] Cited by 15